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KMID : 0358420090520090960
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Korean Journal of Obstetrics and Gynecology
2009 Volume.52 No. 9 p.960 ~ p.965
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Fertility-sparing radical abdominal trachelectomy for cervical clear cell adenocarcinoma unrelated to diethylstilbestrol exposure : A case report
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Kwack Hyun-Sung
Han Ku-Taek
Ha Jae-Eun
Hwang Sun-Jung
Kim Su-Mi
Mon Yong-Ju
Ryu Ki-Sung
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Abstract
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Clear cell adenocarcinoma (CCAC) is a rare cancer that comprises less than 9% of the cervical adenocarcinoma cases. We experienced a case of fertility-sparing radical abdominal trachelectomy for cervical clear cell adenocarcinoma (CCAC). Thus, reported it. A 27 year old female was diagnosed with clinical stage Ib cervical CCAC. She had no history of maternal exposure to diethylstilbestrol and had negative PAP cytology and HPV tests. She was treated with neoadjuvant chemotherapy followed by radical abdominal trachelectomy. After 2 cycles of postoperative adjuvant chemotherapy, the lesion disappeared completely in an imaging study, and potential fertility was preserved. Radical abdominal trachelectomy with chemotherapy may be a valuable approach for treating stage Ib cervical CCAC in women that wish to preserve potential fertility.
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KEYWORD
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Clear cell adenocarcinoma, Cervical cancer, Radical abdominal trachelectomy, diethylstilbestrol
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